2026.07 Release Notes
ASKCOS Development
Software package for the prediction of feasible synthetic routes towards a desired compound and associated tasks related to synthesis planning. Originally developed under the DARPA Make-It program and now being developed under the MLPDS Consortium.
askcos2_core
- update buyable count for 2026.07 (MR mlpds_mit/askcosv2/askcos2_core!169)
- Add guest login configuration to .env.example (MR mlpds_mit/askcosv2/askcos2_core!167)
- port mongo command fix from deploy repo (MR [mlpds_mit/askcosv2/askcos2_core!164] (https://gitlab.com/mlpds_mit/askcosv2/askcos2_core/-/merge_requests/164))
- Update for 2026.07 (MR mlpds_mit/askcosv2/askcos2_core!163)
- Remove unnecessary deletion of buyable_pfpbits (MR mlpds_mit/askcosv2/askcos2_core!162)
- add historian and reactions for higher level (MR mlpds_mit/askcosv2/askcos2_core!161)
- check db data download for update too (MR mlpds_mit/askcosv2/askcos2_core!160)
- add higher level template set to download (MR mlpds_mit/askcosv2/askcos2_core!159)
- Fix .env by correcting chatbot prompt backtick formatting and updating the Keycloak server URL (MR mlpds_mit/askcosv2/askcos2_core!158)
askcos-vue-nginx
- feature(Login): introduce environment setting to disable guest access (Issue mlpds_mit/askcosv2/askcos-vue-nginx#395)
- View Tree / View in IPP breaks single page consistency (Issue mlpds_mit/askcosv2/askcos-vue-nginx#393)
- Fixed IPP expansion error (MR mlpds_mit/askcosv2/askcos-vue-nginx!290)
askcos_deploy
- update buyable count for 2026.07 (MR mlpds_mit/askcosv2/askcos2_deploy!60)
- Update chemspace buyables file to 2026 July in deploy script (MR mlpds_mit/askcosv2/askcos2_deploy!59)
- Feature/rework run mongo (MR mlpds_mit/askcosv2/askcos2_deploy!57)
- Update for 2026.07 (MR mlpds_mit/askcosv2/askcos2_deploy!56)
- propogate default query batch size from core for fastsolv (MR mlpds_mit/askcosv2/askcos2_deploy!55)
- add historian and reactions for higher level (MR mlpds_mit/askcosv2/askcos2_deploy!54)
- add seeding for higher level template sets (MR mlpds_mit/askcosv2/askcos2_deploy!53)
- Fix .env by correcting chatbot prompt backtick formatting and updating the Keycloak server URL (MR mlpds_mit/askcosv2/askcos2_deploy!52)
Deployment
We currently support two methods for deploying ASKCOS: Docker Compose (recommended) and Kubernetes (limited support). Docker Compose is a simpler method for deploying on a single workstation, while Kubernetes is more complex but is suitable for scaling across multiple nodes.
Hardware and Software Requirements
Please review the hardware and software requirements before proceeding to install ASKCOSv2.
Deployment options
ASKCOS is highly modularized and can be installed locally in two ways (click the links for installation instructions):
Upgrade Information
ASKCOSv2 can be easily upgraded by following the instructions here.
Member companies can find more deployment options on the members site